The movie industry is known for bringing together attractive people to act out love stories. So, it’s no surprise that real-life romances often start on set, even when one or both people are already in relationships. The following films played a big role in ending some of Hollywood’s most famous romances and starting new ones.

The Rum Diary

Johnny Depp and Amber Heard, one of the most notorious Hollywood couples of the 21st century, met on the set of *The Rum Diary* in 2011. Soon after, Depp ended his long-term relationship with Vanessa Paradis. He married Heard in 2015, but just 15 months later, Heard filed for divorce, leading to a highly publicized and messy breakup.